ʻO nā paipu ʻohi kokome ka anticoagulant i loko o ka paipu
1 ʻO nā paipu hōʻiliʻili koko i loaʻa ka sodium heparin a i ʻole lithium heparin: ʻO Heparin kahi mucopolysaccharide i loaʻa i kahi pūʻulu sulfate me ka hoʻopiʻi maikaʻi ʻole ikaika, nona ka hopena o ka hoʻoikaika ʻana i ka antithrombin III e hoʻopau i ka serine protease, a laila e pale ai i ka hoʻokumu ʻana o ka thrombin, a loaʻa nā hopena anticoagulant e like me ka pale ʻana. platelet aggregation.Hoʻohana maʻamau ʻia nā paipu Heparin no ka biochemical pilikia a me ke kahe koko, a ʻo ia ke koho maikaʻi loa no ka ʻike electrolyte.Ke hoʻāʻo nei i nā ion sodium i nā hoʻohālike koko, ʻaʻole pono e hoʻohana ʻia ka sodium heparin, i ʻole e hoʻopilikia i nā hopena hōʻike.ʻAʻole hiki ke hoʻohana ʻia no ka helu leukocyte a me ka hoʻokaʻawale ʻana, no ka mea hiki i ka heparin ke hoʻoulu i ka leukocyte aggregation.
2 ʻO nā paipu hōʻiliʻili koko i loaʻa iā EDTA a me kāna mau paʻakai (EDTA—): ʻO EDTA kahi amino polycarboxylic acid, hiki ke hoʻokaʻawale maikaʻi i nā ion calcium i loko o ke koko, a ʻo ka chelating calcium e wehe i ka calcium mai ka calcium.ʻO ka wehe ʻana o ka wahi pane e pale a hoʻopau i ke kaʻina coagulation endogenous a i ʻole extrinsic, e pale ai i ka coagulation koko.Ke hoʻohālikelike ʻia me nā anticoagulants ʻē aʻe, ʻaʻole i emi ka hopena i ka coagulation o nā pūnaewele koko a me ka morphology o nā ʻāpana koko, no laila hoʻohana mau ʻia ka paʻakai EDTA.(2K, 3K, 2Na) ma ke ʻano he anticoagulants.Hoʻohana ʻia ia no nā hoʻokolohua hematological maʻamau, ʻaʻole hiki ke hoʻohana ʻia no ka coagulation koko, trace element a me nā hoʻokolohua PCR.
3 ʻO nā paipu hōʻiliʻili koko i loaʻa ka sodium citrate anticoagulant: Hoʻokani ka sodium citrate i kahi hopena anticoagulant ma o ka hana ʻana i ka chelation o nā ion calcium i loko o ke koko.ʻO ka ratio o ka mea hana i ke koko he 1: 9, a ua hoʻohana nui ʻia i ka ʻōnaehana fibrinolytic (ka manawa prothrombin, ka manawa thrombin, ka manawa o ka thrombin partial, fibrinogen).Ke hōʻiliʻili i ke koko, e hoʻolohe i ka nui o ke koko i hōʻiliʻili ʻia e hōʻoia i ka pololei o nā hopena hōʻike.Ma hope koke o ka hōʻiliʻili ʻana i ke koko, pono e hoʻohuli ʻia a hui pū ʻia i nā manawa 5-8.
4 Loaʻa i ka sodium citrate, ʻo ka neʻe o ka sodium citrate he 3.2% (0.109mol/L) a me 3.8%, ʻo ka nui o ka lākiō o ka anticoagulant i ke koko he 1:4, hoʻohana maʻamau no ka ʻike ESR, kiʻekiʻe loa ka hapa o ka anticoagulant. he kiʻekiʻe, hoʻoheheʻe ʻia ke koko, hiki ke hoʻolalelale i ka erythrocyte sedimentation rate.
5 Aia i loko o ka pahu ka potassium oxalate/sodium fluoride (1 ʻāpana o ka sodium fluoride a me 3 ʻāpana o ka potassium oxalate): ʻO ka sodium fluoride he anticoagulant nāwaliwali, he hopena maikaʻi ia i ka pale ʻana i ke kō koko, a he mea mālama maikaʻi loa ia no ka ʻike ʻana i ke kō koko. .Pono e hoʻohuli a hui mālie i ka wā e hoʻohana ai.Hoʻohana maʻamau ia no ka ʻike ʻana i ke kō koko, ʻaʻole no ka hoʻoholo ʻana i ka urea ma ke ʻano urease, ʻaʻole no ka ʻike ʻana i ka alkaline phosphatase a me ka amylase.
Hiki iā mākou ke hāʻawi iā ʻoe i nā huahana pili.
Ka manawa hoʻouna: ʻAukake-19-2022
