Chubu chotolera magaziali ndi anticoagulant
1) magazi zosonkhanitsira chubu munali heparin sodium kapena heparin lifiyamu: heparin ndi mucopolysaccharide munali sulfate gulu, ndi amphamvu zoipa mlandu, amene ali ndi ntchito yolimbikitsa antithrombin III kuti inactivate serine protease, motero kupewa mapangidwe thrombin, ndi kuteteza kupatsidwa zinthu za m`mwazi aggregation ndi zotsatira zina za anticoagulant.Heparin chubu nthawi zambiri amagwiritsidwa ntchito pozindikira zadzidzidzi za biochemistry ndi rheology yamagazi, ndipo ndiye chisankho chabwino kwambiri chozindikira ma electrolyte.Poyesa ayoni a sodium m'magazi, heparin sodium sangathe kugwiritsidwa ntchito, kuti asakhudze zotsatira za mayeso.Singagwiritsidwenso ntchito powerengera ndi kugawa maselo oyera a magazi, chifukwa heparin imayambitsa kuphatikizika kwa maselo oyera a magazi.
2) Kusonkhanitsa mitsempha ya magazi munali ethylenediaminetetraacetic asidi ndi mchere wake (EDTA -): ethylenediaminetetraacetic asidi ndi amino polycarboxylic acid, amene mogwira chelate calcium ayoni m'magazi.Kashiamu wa chelated amachotsa kashiamu pamalo omwe amachitira, zomwe zingalepheretse ndikuthetsa njira yamkati kapena yakunja ya coagulation, motero kupewa kutsekeka kwa magazi.Poyerekeza ndi anticoagulants ena, ali ndi mphamvu zochepa pa agglutination wa maselo a magazi ndi morphology ya maselo a magazi, Choncho, Desheng EDTA mchere (2K, 3K, 2Na) nthawi zambiri ntchito ngati anticoagulants.Amagwiritsidwa ntchito poyesa magazi wamba, koma osati pakupanga magazi, kufufuza zinthu ndi kuyezetsa PCR.
3) Machubu osonkhanitsira magazi okhala ndi sodium citrate anticoagulant: sodium citrate imagwira ntchito ya anticoagulant pochita pa calcium ion chelation mu zitsanzo za magazi.National Committee for Clinical Laboratory Standardization (NCCLS) imalimbikitsa 3.2% kapena 3.8%, ndipo chiŵerengero cha anticoagulant ndi magazi ndi 1: 9.Amagwiritsidwa ntchito kwambiri mu fibrinolysis system (nthawi ya prothrombin, nthawi ya thrombin, nthawi yokhazikika ya thrombin, fibrinogen).Mukatenga magazi, samalani kuti mutenge magazi okwanira kuti muwonetsetse kuti zotsatira za mayeso ndizolondola.Mutatenga magazi, iyenera kusinthidwa nthawi yomweyo ndikusakaniza nthawi 5-8.
4) Chubucho chimakhala ndi potaziyamu oxalate/sodium fluoride (gawo limodzi la sodium fluoride ndi magawo atatu a potaziyamu oxalate): sodium fluoride ndi anticoagulant yofooka, imakhala ndi zotsatira zabwino poletsa kuwonongeka kwa shuga m'magazi, ndipo imateteza kwambiri kuzindikirika kwa shuga m'magazi. .Mukamagwiritsa ntchito, ziyenera kusakanikirana mozondoka pang'onopang'ono.Amagwiritsidwa ntchito pozindikira kuchuluka kwa shuga m'magazi, osati kudziwa urea pogwiritsa ntchito njira ya urease, komanso kudziwa za alkaline phosphatase ndi amylase.
Nthawi yotumiza: Sep-21-2022
