Paipu ʻohi kokoloaʻa ka anticoagulant
1) ʻO ka pahu hōʻiliʻili koko i loaʻa ka heparin sodium a i ʻole heparin lithium: ʻo ka heparin he mucopolysaccharide i loaʻa i ka pūʻulu sulfate, me ka hoʻopiʻi maikaʻi ʻole ikaika, nona ka hana o ka hoʻoikaika ʻana i ka antithrombin III e hoʻopau i ka serine protease, pēlā e pale ai i ka hoʻokumu ʻana o ka thrombin, a pale i ka platelet aggregation a nā hopena anticoagulant ʻē aʻe.Hoʻohana maʻamau ʻo Heparin tube no ka ʻike ʻana i ka biochemistry pilikia a me ka rheology koko, a ʻo ia ke koho maikaʻi loa no ka ʻike electrolyte.I ka hoʻāʻo ʻana i nā ion sodium i nā hoʻohālike koko, ʻaʻole hiki ke hoʻohana ʻia ka sodium heparin, i ʻole e hoʻopilikia i nā hopena hōʻike.ʻAʻole hiki ke hoʻohana ʻia no ka helu ʻana a me ka hoʻokaʻawale ʻana o ke koko keʻokeʻo, no ka mea, ʻo ka heparin ka mea e hoʻohui ai i ke koko keʻokeʻo.
2) ʻO ka ʻohi ʻana i nā kīʻaha koko i loaʻa ka ethylenediaminetetraacetic acid a me kāna paʻakai (EDTA -): ʻo ka ethylenediaminetetraacetic acid he amino polycarboxylic acid, hiki ke hoʻokaʻawale maikaʻi i nā ion calcium i loko o ke koko.E hoʻoneʻe ka calcium chelated i ka calcium mai ka wahi pane, e pale a hoʻopau i ke kaʻina coagulation endogenous a i ʻole exogenous, pēlā e pale ai i ka coagulation koko.Ke hoʻohālikelike ʻia me nā anticoagulants ʻē aʻe, he liʻiliʻi ka hopena i ka agglutination o nā keʻena koko a me ka morphology o ke koko koko, no laila, hoʻohana mau ʻia nā paʻakai Desheng EDTA (2K, 3K, 2Na) e like me nā anticoagulants.Hoʻohana ʻia ia no ka hoʻokolokolo hematological maʻamau, akā ʻaʻole no ka coagulation koko, trace element a me ka hoʻokolokolo PCR.
3) ʻO nā paipu hōʻiliʻili koko i loaʻa ka sodium citrate anticoagulant: pāʻani ka sodium citrate i kahi hana anticoagulant ma o ka hana ʻana i ka chelation ion calcium i nā laʻana koko.Manaʻo ka National Committee for Clinical Laboratory Standardization (NCCLS) i ka 3.2% a i ʻole 3.8%, a ʻo ka ratio o ka anticoagulant i ke koko he 1:9.Hoʻohana nui ʻia ia i ka ʻōnaehana fibrinolysis (ka manawa prothrombin, ka manawa thrombin, ka manawa o ka thrombin partial, fibrinogen).I ka lawe ʻana i ke koko, e makaʻala i ka lawe ʻana i ke koko e hōʻoia i ka pololei o nā hopena hōʻike.Ma hope o ka lawe ʻana i ke koko, pono e hoʻohuli koke ʻia a hui pū ʻia i 5-8 mau manawa.
4) Aia ka pāpaʻa oxalate / sodium fluoride (1 ʻāpana sodium fluoride a me 3 mau ʻāpana potassium oxalate): ʻo ka sodium fluoride he anticoagulant nāwaliwali, he hopena maikaʻi i ka pale ʻana i ka hōʻino ʻana o ka glucose koko, a he mea mālama maikaʻi loa ia no ka ʻike koko glucose. .I ka hoʻohana ʻana, pono e hui mālie ʻia i luna i lalo.Hoʻohana maʻamau ia no ka ʻike ʻana i ka glucose koko, ʻaʻole no ka hoʻoholo ʻana i ka urea ma ke ʻano urease, ʻaʻole no ka alkaline phosphatase a me ka ʻike amylase.
Ka manawa hoʻouna: Sep-21-2022
