Ishubhu yokuqoqa igaziiqukethe i-anticoagulant
1) Ishubhu lokuqoqa igazi eliqukethe i-heparin sodium noma i-heparin lithium: i-heparin iyi-mucopolysaccharide equkethe iqembu le-sulfate, enecala elibi elinamandla, elinomsebenzi wokuqinisa i-antithrombin III ukuze yenze i-serine protease ingasebenzi, ngaleyo ndlela ivimbele ukwakheka kwe-thrombin, futhi ivimbele ukuhlangana kweplatelet kanye eminye imiphumela ye-anticoagulant.I-Heparin tube ngokuvamile isetshenziselwa ukutholwa kwe-biochemistry ephuthumayo kanye ne-rheology yegazi, futhi iyisinqumo esingcono kakhulu sokutholwa kwe-electrolyte.Lapho kuhlolwa i-sodium ion kumasampula egazi, i-heparin sodium ayikwazi ukusetshenziswa, ukuze ingaphazamisi imiphumela yokuhlolwa.Angeke futhi isetshenziselwe ukubala amangqamuzana egazi amhlophe kanye nokuhlukaniswa, ngoba i-heparin izobangela ukuhlangana kwamangqamuzana egazi amhlophe.
I-2) Ukuqoqa imithambo yegazi equkethe i-ethylenediaminetetraacetic acid kanye nosawoti wayo (EDTA -): i-ethylenediaminetetraacetic acid i-amino polycarboxylic acid, engakwazi ukuhlanza kahle i-calcium ions egazini.I-calcium e-chelated izosusa i-calcium endaweni yokusabela, ezovimbela futhi iqede inqubo ye-endogenous noma exogenous coagulation, ngaleyo ndlela ivimbele ukuhlangana kwegazi.Uma kuqhathaniswa namanye ama-anticoagulants, anomthelela omncane ekuhlanganisweni kwamangqamuzana egazi kanye nokwakheka kwamangqamuzana egazi, Ngakho-ke, usawoti we-Desheng EDTA (2K, 3K, 2Na) uvame ukusetshenziswa njengama-anticoagulant.Isetshenziselwa ukuhlolwa kwegazi okujwayelekile, kodwa hhayi ekuhlanganiseni kwegazi, i-trace element kanye nokuhlolwa kwe-PCR.
3) Amashubhu okuqoqa igazi aqukethe i-sodium citrate anticoagulant: i-sodium citrate idlala indima ye-anticoagulant ngokusebenza nge-calcium ion chelation kumasampula egazi.I-National Committee for Clinical Laboratory Standardization (NCCLS) itusa u-3.2% noma u-3.8%, kanti isilinganiso se-anticoagulant negazi singu-1:9.Isetshenziswa kakhulu ohlelweni lwe-fibrinolysis (isikhathi se-prothrombin, isikhathi se-thrombin, isikhathi se-thrombin esicushiwe, isikhathi se-fibrinogen).Lapho uthatha igazi, naka ukuthatha igazi elanele ukuze uqinisekise ukunemba kwemiphumela yokuhlolwa.Ngemuva kokuthatha igazi, kufanele liguqulwe ngokushesha futhi lixutshwe izikhathi ezingama-5-8.
4) Ishubhu iqukethe i-potassium oxalate/sodium fluoride (ingxenye engu-1 ye-sodium fluoride nezingxenye ezi-3 ze-potassium oxalate): i-sodium fluoride iyi-anticoagulant ebuthakathaka, inomthelela omuhle ekuvimbeleni ukuwohloka koshukela osegazini, futhi iyisilondolozi esihle kakhulu sokutholwa kweglucose egazini. .Lapho uyisebenzisa, kufanele ixutshwe ngokucophelela ibheke phansi kancane.Ngokuvamile isetshenziselwa ukutholwa kweglucose yegazi, hhayi ekunqumeni i-urea ngendlela ye-urease, noma ekutholweni kwe-alkaline phosphatase kanye ne-amylase.
Isikhathi sokuthumela: Sep-21-2022
